Bioinformatician

Einsatzort: Freiburg

MPI

Art der Stelle

Bioinformatician

Stellenangebot vom 05.01.2018

A Bioinformatician position will be available in the Jenuwein group at the Max Planck Institute of Immunobiology and Epigenetics in Freiburg, Germany). The Jenuwein group studies molecular mechanisms that establish and maintain heterochromatin in mammalian cells. There is a particular focus on the genome-wide regulation of repetitive element expression during mouse ES cell differentiation and in disease using a variety of experimental and next generation sequencing approaches. For these genome-wide analyses, we seek an experienced bioinformatician, preferably with previous interest in chromatin biology and epigenetic control mechanisms. This Bioinformatician position is open immediately and initially funded for two years, with the possibility of extension.

The Max Planck Institute of Immunobiology and Epigenetics (MPI-IE) in Freiburg, Germany is an interdisciplinary research institution that conducts basic research in two key areas of modern biology: Immunobiology and Epigenetics. Central questions address the molecular basis of cell type identities, as they are regulated during immune cell differentiation, metabolic response and epigenetic chromatin adaptation.

Your opportunities

As an embedded bioinformatician, you will have the opportunity to contribute directly to multiple research projects, from experimental design to data analysis and interpretation. This position also offers additional opportunities for participating in the Collaborative Research Center “Medical Epigenetics” (MEDEP). You will also interact with a strong, interdisciplinary bioinformatics and deep sequencing facility that provides access to a large Sequencing Facility (HiSeq3000, HiSeq2500, NextSeq), as well as a high-performance Data Center with Petabyte-scale storage solutions.

Your tasks

Responsibilities include the bioinformatics analysis of genome-wide datasets, such as ChIP-seq and RNA-seq, as well as transcription factor motif analysis and analysis of other next-generation sequencing-based experiments. A strong understanding of epigenetic mechanisms of gene regulation will also be necessary, in order to process, analyze, and interpret a variety of datasets, focusing particularly on repetitive DNA elements and chromatin modifying factors.

Your qualifications

We are looking for a dedicated and motivated team player with strong communication skills and good command of the English language, who has a MSc or PhD degree in bioinformatics or equivalent experience in a related field. The successful applicant will have proven experience in the analysis of genome-wide datasets and computational skills (python/perl, R/Bioconductor) in a Linux environnment. Knowledge of alignment programs (such as STAR), RepeatMasker, and data analysis and visualization tools in R will be necessary. A profound interest in epigenetics and repetitive DNA regulation will also be required.

Our offer

Based within a region that connects Germany, France and Switzerland, our institute hosts a vibrant community of international researchers, state-of-the-art facilities, and modern office spaces. At the heart of the Black Forest, Freiburg offers a family-friendly atmosphere and excellent recreational possibilities for cultural and outdoor activities.

Salary will be based on previous experience according to TVöD guidelines.

Handicapped applicants with equal qualifications will be given preferential treatment. The Max Planck Society seeks to increase the number of women in areas, where they are underrepresented, and therefore explicitly encourages women to apply. A childcare facility is directly attached to the institute.

Application

Have we sparked your interest? Please submit your complete application, including a CV, a 1 page motivation summary and contact details of referees via our online application portal until February 15th,  2018.

For informal inquiries please contact: .

Max Planck Institute of Immunobiology and Epigenetics
Stübeweg 51
79108 Freiburg
Germany

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