Doctoral Researcher (f/div/m) Molecular and Applied Microbiology

Einsatzort: Jena

Job Advertisement Leibniz-HKI-39/2021

The Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute - (Leibniz-HKI, investigates the pathobiology of human-pathogenic fungi and identifies targets for the development of novel natural product-based antibiotics. The department of Molecular and Applied Microbiology invites talented and highly gifted candidates to apply as a

Doctoral Researcher (f/div/m) Molecular and Applied Microbiology

starting from October 2021 for three years initially.

The successful candidate will work within the framework of a DFG-funded Collaborative Research Center / Transregio 124 "FungiNet" on the surface proteins of the human-pathogenic fungi Lichtheimia corymbifera and Aspergillus fumigatus as virulence determinant.

Main topics of the project may include:

  • Elucidation of the mechanisms allowing for long-term survival of spores in the phagosome of macrophages
  • Genetic, proteomic and microscopic characterization of phagosomes containing spores of L. corymbifera and A. fumigatus
  • Characterization of spore and host proteins involved in delayed phagosome maturation
  • Screening and testing of compounds that interfere with the phagosome maturation process

Our requirements:

We expect a master´s degree in natural sciences/life sciences (Microbiology, Cell Biology, Biochemistry, Molecular Biology). Good knowledge in standard techniques of microbiology, immunology, biochemistry and molecular biology is expected. Experience in cell culture, fluorescence microscopy and CRISPR/Cas-methods would be preferable. We would welcome a highly motivated co-worker with excellent communications skills and the ability to work on a cooperative project.

We offer

you a multifaceted scientific project, which involves cooperation within a Collaborative Research Center, state-of-the-art instrumentation, and great work opportunities in a dynamic research institute with high reputation. The PhD candidate will participate in the structured program of the Jena School for Microbial Communication. The successful candidate will be hosted in the department Molecular and Applied Microbiology.

Salary is paid according to German TV-L (salary agreement for public service employees). As an equal opportunity employer, the Leibniz-HKI is committed to increasing the percentage of female scientists and therefore especially encourages them to apply. The anticipated start date is November 1st, 2021.

For further information:

Prof. Dr. Axel Brakhage | +49 3641 532 1071 |


Complete applications in English should include a cover letter, a CV containing a complete list of publications, a brief statement of research experiences, the addresses of two possible referees, and should be submitted by September 12, 2021, via the Leibniz-HKI online application system.