- Structural and Cell Biology
- Complex Systems
Art der Stelle
Master Thesis / Internship (m/f/d) in Molecular Biology and Upstream Processing
Stellenangebot vom 08.05.2020
The Department of Bioprocess Engineering at the Max Planck Institute for Dynamics of Complex Technical Systems in Magdeburg is looking for a master student (m/f/d) in the field of molecular biology/upstream processing. The topic of the work is “Evolution of influenza A virus defective interfering particles in a continuous culture”.
Annually, up to 650 000 people die worldwide from an influenza A virus infection. Since influenza A virus often show resistance to typical antiviral drugs, new treatment approaches are needed. One promising antiviral agent are defective interfering particles (DIPs). They are randomly created during Influenza A virus (IAV) replication and comprise a deletion in the viral genome. Moreover, DIPs interfere with the replication of the infectious standard virus (STV) in a co-infection.
We aim to use the two-stage cultivation system to study the evolution of IAV DIPs. In this master thesis, a broad spectrum of methods can be learned (cell culture, virus production, virus quantification (e.g plaque assay, real-time RT-qPCR), analysis of next-generation sequencing data).
The candidate (m/f/d) will have access to state-of-the-art instrumentation and laboratory equipment at our Max Planck Institute in an international group of researchers.
- Master student (m/f/d) in biotechnology, bio-process engineering, technical biology, or life science
- Lab experience with sterile cell culture, ideally in the following domains: mammalian cell culture, virus production
- Motivation, curiosity and team work skills
- Good scientific English level
When to start:
From mid ot end of 2020.
How to apply:
Send your CV, reference letters, a motivation letter and the list of attended courses with your grades (university and high school) to the contact.
Phone: +49 391 6110 224
The Max Planck Society is committed to increasing the number of individuals with disabilities in its workforce and therefore encourages applications from such qualified individuals. Furthermore, the Max Planck Society seeks to increase the number of women in those areas where they are underrepresented and therefore explicitly encourages women to apply.
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