- Structural and Cell Biology
- Complex Systems
Art der Stelle
Master Thesis / Internship (m/f/d) | Molecular Biology
Stellenangebot vom 08.07.2021
The Department of Bioprocess Engineering at the Max Planck Institute for Dynamics of Complex Technical Systems in Magdeburg is looking for a master student (m/f/d) in the field of molecular biology. The topic of the work is:
“Respiratory syncytial virus replication: Inhibition by Influenza A virus defective interfering particles”
Infections with respiratory syncytial virus (RSV) are the main cause of illness in hospitalized children under 2 years of age. However, neither vaccines nor curative antiviral drugs are currently approved. One promising antiviral agent are defective interfering particles (DIPs). They are randomly created during viral replication and comprise a deletion in the viral genome. DIPs of influenza A virus (IAV) have been suggested for antiviral therapy of the influenza disease, but also for diseases caused by heterogeneous viruses (such as SARS-CoV-2) due to the activation of the innate immune response. Thus, IAV DIPs might also show an inhibitory effect against the RSV propagation.
In this project, we aim to perform co-infection studies with IAV DIPs and RSV to investigate the use of IAV DIPs for antiviral therapy. A broad spectrum of methods can be learned (cell culture, virus production, virus quantification (e.g plaque assay, real-time RT-qPCR), protein quantification (ELISA), immunofluorescence staining.
The candidate (m/f/d) will have access to state-of-the-art instrumentation and laboratory equipment at our Max Planck Institute in an international group of researchers.
- Master student (m/f/d) in molecular biology, molecular medicine, biochemistry, genetics, biotechnology, life science or related fields
- Lab experience with sterile cell culture, ideally in the following domains: mammalian cell culture, qPCR, plaque assay
- Motivation, curiosity and team work skills
- Good scientific English level
When to start
This position can be started as soon as possible.
How to apply
Send your CV, reference letters, a motivation letter and the list of attended courses with your grades (university and high school) to the contact.
The Max Planck Society is committed to increasing the number of individuals with disabilities in its workforce and therefore encourages applications from such qualified individuals. Furthermore, the Max Planck Society seeks to increase the number of women in those areas where they are underrepresented and therefore explicitly encourages women to apply.
Phone: +49 391 6110 224
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