PostDoc New Chemical Entities Formulation Sciences Biopharmaceutical Method Development – temporary

Einsatzort: Ludwigshafen

PostDoc New Chemical Entities Formulation Sciences Biopharmaceutical Method Development  – temporary

PostDoc New Chemical Entities Formulation Sciences Biopharmaceutical Method Development – temporary

Research project: Opportunities of artificial gastrointestinal models in biopharmaceutical method development and its impact on oral drug formulation development

The Pharmaceutics Team within NCE Formulation Sciences department is seeking a motivated Post-Doctoral Fellow with a strong interest in better understanding the opportunities and limitations of available biopharmaceutic methods. Specifically, the selected candidate will be involved in:

  • Establishing new and improving existing biopharmaceutics methods to study the behavior of orally administered drugs in the GIT
  • Method development for analytical characterization of the samples processed by in vitro dissolution assays
  • Evaluation of physico-chemical characteristics of active pharmaceutical ingredients (API) and corresponding formulation prototypes in order to select the suitable bio relevant in vitro method
  • Comparison of in vitro data with in vivo data with regard to pharmacokinetic parameters
  • Process optimization in analytics and formulation development using Design of Experiments methodology
  • Drive innovative science, monitor or conduct experiments and studies, to advance projects or technologies
  • Supervision of students and pharmaceutics interns in scientific initiatives
  • Sharing information and presenting results in globally acting teams
  • Description of experiments, presentation and assessment of results in reports and publications as well as documentation of the gained knowledge in SOPs

Temporary position for 24 month.


  • PhD in natural sciences, preferably with a background in pharmacy, pharmacology, analytical chemistry, biochemistry, biology, biotechnology or related field
  • Demonstrated skills in analytical characterization of new chemical entities (especially drug release and HPLC/UPLC)
  • Experience with gastro-intestinal testing with the TNO gastroIntestinal Models (TIM) preferable
  • Strong knowledge in pharmacokinetics and pharmacodynamics methodologies
  • Knowledge in pharmaceutical technology and formulation
  • Ability to develop, design, execute and manage complex research programs
  • Proficient in data analysis, quantitative techniques
  • Strong analytical mind with good problem solving and writing skills
  • Fluent in English, German is a plus
  • Team player with excellent organizational and communication/presentation skills
  • Ability to interact and establish positive interaction with internal/external customers
  • Highly motivated and independent, organized and result-oriented

We are looking forward to your application. Please provide information about your salary expectations and possible start date in your motivation letter.
 
An equal opportunity employer. AbbVie welcomes and encourages diversity in our workforce.
 
Learn more about AbbVie Deutschland at www.abbvie.de  Visit www.abbvie-care.de for more information about the therapeutic areas in which we’re active.


AbbVie (NYSE:ABBV) ist ein globales, forschendes BioPharma-Unternehmen, das sich der Entwicklung innovativer Therapien für einige der komplexesten und schwerwiegendsten Erkrankungen der Welt verschrieben hat. Mission des Unternehmens ist es, mit seiner Expertise, seinen engagierten Mitarbeitern und seinem Innovationsanspruch die Behandlungsmöglichkeiten in vier Therapiegebieten deutlich zu verbessern: Immunologie, Onkologie, Virologie und Neurowissenschaften. In mehr als 75 Ländern arbeiten AbbVie-Mitarbeiter jeden Tag daran, die Gesundheitsversorgung für Menschen auf der ganzen Welt voranzutreiben. In Deutschland ist AbbVie an seinem Hauptsitz in Wiesbaden und seinem Forschungs- und Produktionsstandort in Ludwigshafen vertreten. Insgesamt beschäftigt AbbVie Deutschland rund 2.600 Mitarbeiter. Mit rund 29.000 Mitarbeitern weltweit vertreibt AbbVie Medikamente in mehr als 170 Länder.